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Neurocutaneous syndromes

Clinical Child Neurology, Page: 327-355
2020
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Book Chapter Description

Neurocutaneous syndromes comprise diagnoses that affect the nervous system and skin on the basis of common embryologic origin from ectoderm. Abnormal cell proliferation and organization can manifest as tumor potential or vascular abnormalities in multiple locations; these can produce symptoms across the life span. An understanding of the natural history has guided recommendations to screen affected individuals and at-risk family members. With increasing research at a genetic and pathophysiologic level, there has been improved availability of treatment options not only for these specific conditions but others as well.

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