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Sexual dimorphism and estrogen action in mouse liver

Advances in Experimental Medicine and Biology, ISSN: 2214-8019, Vol: 1043, Page: 141-151
2017
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Book Chapter Description

Recent studies have demonstrated that in mice, the estrogen receptor alpha (ERα) is expressed in the liver and has a direct effect on the regulation of the hepatic genes relevant for energy metabolism and drug metabolism. The sex-related differential expression of the hepatic ERα raises the questions as to whether this receptor is responsible for the sexual differences observed in the physiopathology of the liver.

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