Geroscience
Aging Research - Methodological Issues: Second Edition, Page: 55-62
2018
- 92Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Captures92
- Readers92
- 92
Book Chapter Description
Geroscience is an emerging discipline that examines the relationship between biological mechanisms of aging across different species with the goal of understanding the molecular and cellular pathways underlying age-related diseases. Geroscience is based upon finding connections between the so called "hallmarks of aging", a term that refers to stress adaptation, epigenetics, inflammation, macromolecular damage, metabolism, proteostasis, stem cells and regeneration as well as nutrient sensing to elucidate processes damaged in chronic diseases highly prevalent in older people. In this chapter, we tried to explain the origins of Geroscience, its relevance to the study of aging and its connection to disease, as well as to emphasize specific experimental findings that resulted from studies of animal models focused in replicating the physiopathological features of age-related diseases such as neurodegenerative and cardiovascular diseases, sarcopenia and osteoporosis, cancer, diabetes and frailty. Finally, we discussed some potential biomarkers suggested to improve the diagnosis or accelerate the identification of therapeutic targets in order to minimize the negative impact of chronic diseases during aging.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85062945949&origin=inward; http://dx.doi.org/10.1007/978-3-319-95387-8_4; http://link.springer.com/10.1007/978-3-319-95387-8_4; http://link.springer.com/content/pdf/10.1007/978-3-319-95387-8_4; https://dx.doi.org/10.1007/978-3-319-95387-8_4; https://link.springer.com/chapter/10.1007/978-3-319-95387-8_4
Springer Nature America, Inc
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