Whole-body applications of DWI
Diffusion MRI Outside the Brain: A Case-Based Review and Clinical Applications, Vol: 9783642210525, Page: 365-393
2012
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Book Chapter Description
DWI has revealed great potential in cancer and bone marrow imaging of the body. Whole-body DWI is a recent application, performing multiple stations and a composite image of the entire body. The true utility of WB-DWI has shown the potential and clinical values of this emerging technique for oncologic as well as for nononcologic applications. A complete WB-MRI protocol with standard sequences, DWI, and dynamic 3D contrast-enhanced acquisitions can be performed in less than 40 min of examination. WB-DWI has focused on the detection of osseous metastases in patients with primary malignancies that had the potential to metastasize to the skeletal system and multiple myeloma, and also in the evaluation of the therapeutic response in human bone marrow. WB-DWI is superior to bone scan and PET in the evaluation of bone marrow tumoral involvement. WB-DWI provides also additional information of the extraskeletal areas. DWI is useful to quantify the results with the ADC values, with several clinical applications such as the differentiation between acute benign fractures from malignant and infectious lesions. Further research, comparing and evaluating complementary roles of PET and WB-DWI, is still needed
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84928854257&origin=inward; http://dx.doi.org/10.1007/978-3-642-21052-5_16; http://link.springer.com/10.1007/978-3-642-21052-5_16; http://link.springer.com/content/pdf/10.1007/978-3-642-21052-5_16; https://dx.doi.org/10.1007/978-3-642-21052-5_16; https://link.springer.com/chapter/10.1007/978-3-642-21052-5_16
Springer Nature
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