Reconstitution of germ cell development in vitro
Cell Biology of the Ovary: Stem Cells, Development, Cancer, and Clinical Aspects, Page: 1-19
2018
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Book Chapter Description
Mammalian germ cell development begins with the specification of primordial germ cells (PGCs) in the early phase of pregnancy. The development of PGCs to spermatozoa or mature oocytes involves complex pathways and takes a long time, e.g., more than 10 years in humans. Recent researches aimed at reconstituting germ cell development using pluripotent stem cells in vitro have achieved remarkable progress. Establishment of these in vitro systems is of great importance for addressing various biological questions on the nature of germ cells, as well as for studying the associated diseases and potentially for applied research.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85053171244&origin=inward; http://dx.doi.org/10.1007/978-981-10-7941-2_1; http://link.springer.com/10.1007/978-981-10-7941-2_1; https://dx.doi.org/10.1007/978-981-10-7941-2_1; https://link.springer.com/chapter/10.1007/978-981-10-7941-2_1
Springer Science and Business Media LLC
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