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Non-coding RNAs and Ischemic Cardiovascular Diseases

Advances in Experimental Medicine and Biology, ISSN: 2214-8019, Vol: 1229, Page: 259-271
2020
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Book Chapter Description

The Ischemic Heart Disease (IHD) is considered a clinical condition characterized by myocardial ischemia causing an imbalance between myocardial blood supply and demand, leading to morbidity and mortality across the worldwide. Prompt diagnostic and prognostic represents key factors for the treatment and reduction of the mortality rate. Therefore, one of the newest frontiers in cardiovascular research is related to non-coding RNAs (ncRNAs), which prompted a huge interest in exploring ncRNAs candidates for utilization as potential therapeutic targets for diagnostic and prognostic and/or biomarkers in IHD. However, there are undoubtedly many more functional ncRNAs yet to be discovered and characterized. Here we will discuss our current knowledge and we will provide insight on the roles and effects elicited by some ncRNAs related to IHD.

Bibliographic Details

Smani, Tarik; Mayoral-Gonzalez, Isabel; Galeano-Otero, Isabel; Gallardo-Castillo, Isabel; Rosado, Juan A; Ordoñez, Antonio; Hmadcha, Abdelkrim

Springer Science and Business Media LLC

Biochemistry, Genetics and Molecular Biology

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