A missing dilemma on nanoparticle producer microorganisms

The development of eco-friendly biological methods in material synthesis has been reported with chemically well-defined variety of inorganic nanoparticles (NP) that are produced by using various microorganisms. In last decades, lots of research articles have suggested required conditions to control and particle stability on biosynthesized nanoparticles, besides their applications in a wide spectrum of potential fields including target oriented drug delivery, cancer therapy, gene therapy and DNA based diagnosis, using of antimicrobial agents, biosensors, enhancing enzymatic reaction capacity with advanced medical visualization technology. Even the present limitations and future prospects for the production of inorganic nanoparticles by microorganisms are dramatically studied, their disadvantages in practice concerning their negative effects on micro- and macroorganisms are attracting the attention of researchers. As another concept, the behaviours of microorganism change depending on available concentration of nanomolecules containing inorganic chemical structures in environment affecting their antibacterial compounds secretion. The review highlights particularly ignored or missed cases on the usage of nanoparticle producer microorganisms. We briefly discuss here, as an another concept; enhancing anti-phytopathogen potential capacity of soil can negatively be affected by NP synthesizing microorganisms that may drastically impair microflora balance and its own biocontrol capacity besides in contrary to their expected positive advantages in purpose of their antimicrobial property.