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Microbial Secondary Metabolites: Targeting Tumors and Associated Challenges

Role of Microbes in Sustainable Development: Human Health and Diseases, Page: 429-439
2023
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Book Chapter Description

Secondary metabolites derived from microbes have been utilized for a number of applications in the medical sector for a considerable time. Microbial secondary metabolites (MSMs) are utilized as enzyme inhibitors, immune-suppressants, hypocholesterolemic agents, etc., in the healthcare sector. Owing to their high efficacy and biocompatibility, several MSMs have also been applied for cancer treatment, responsible for major mortality in the world. Plenty of these metabolites are still under clinical trials awaiting large-scale application. This chapter summarizes the current status of tumor-targeting MSMs, recent innovations to elucidate the antitumor mechanism of these metabolites, and exploring potential microbes for the production of novel antitumor metabolites using co-cultivation and omics approaches.

Bibliographic Details

Simran Rani; Pradeep Kumar; Priyanka Dahiya; Pooja Suneja; Amita Suneja Dang

Springer Science and Business Media LLC

Medicine; Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics

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