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Epigenetics of SARS-CoV2 (COVID-19)

Targeting Epigenetics in Inflammatory Lung Diseases, Page: 199-208
2023
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Book Chapter Description

The study of genetic differences in gene activity without alterations to DNA sequences is referred to as “epigenetics.” The focus of this extremely new field of research is on the genetic and non-genetic elements of genetic phenotypic variations. The identification of genetic risk factors for the COVID-19 pandemic is becoming increasingly crucial due to its role as the source of the COVID-19 outbreak. Since the COVID-19 pass in cells of host through the ACE2 receptor, it is suspected that the ACE2 gene serves as a gene-related risk factor for COVID-19 infections. Furin and transmembrane protease serine 2 (TMPRSS2) have a huge effect on illness severity. This chapter compiled the most recent studies showing the mutations, expression, and epigenetic modifiers that may affect a person’s vulnerability to COVID-19 disease and infection prognosis.

Bibliographic Details

Sarita Rawat; Ritu Gilhotra; Santosh Kumar Singh; Asif Ahmad Bhat; Abhijeet Ojha; Karuna Dhaundhiyal; Ishwar Singh Dhramshaktu; Gaurav Gupta

Springer Science and Business Media LLC

Medicine; Pharmacology, Toxicology and Pharmaceutics; Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences

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