Mechanism of Cl sensitivity in internal ion receptors of the leech; an inward current gated off by Cl in the nephridial nerve cells
Journal of Comparative Physiology A, ISSN: 0340-7594, Vol: 168, Issue: 1, Page: 53-61
1991
- 8Citations
- 5Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations8
- Citation Indexes8
- CrossRef5
- Captures5
- Readers5
Article Description
The nephridial nerve cells of the leech, Hirudo medicinalis, 34 sensory cells, each associated with one nephridium, are sensitive to changes in extracellular Cl concentration, an important factor in ion homeostasis. Using single-electrode current- and voltage clamp and ion substitution techniques, the specificity and mechanism of Cl sensitivity of the nephridial nerve cell was studied in isolated preparations. Increase of the normally low external Cl concentration leads to immediate and sustained hyperpolarization, decrease of the frequency of bursts and decrease of membrane conductance. The response is halogen specific: Cl can be replaced by Br, but not by organic mono- or divalent anions or inorganic divalent anions. At physiological Cl concentrations (36m M extra-cellular Cl), the nephridial nerve cell has a high resting conductance for Cl and the membrane potential is governed by Cl. In high extracellular Cl concentrations (110-130 m M), membrane conductance is low, most likely due to the gating off of Cl channels. Under these conditions, membrane potential is dominated by the K distribution and the nephridial nerve cell hyperpolarizes towards E. © 1991 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0026021776&origin=inward; http://dx.doi.org/10.1007/bf00217103; http://www.ncbi.nlm.nih.gov/pubmed/2033568; http://link.springer.com/10.1007/BF00217103; http://www.springerlink.com/index/pdf/10.1007/BF00217103; https://dx.doi.org/10.1007/bf00217103; https://link.springer.com/article/10.1007/BF00217103; http://www.springerlink.com/index/10.1007/BF00217103
Springer Science and Business Media LLC
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know