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A morphometric study of sub-cellular organization in mouse mammary cancers and normal lactating tissue

Zeitschrift für Zellforschung und Mikroskopische Anatomie, ISSN: 0302-766X, Vol: 87, Issue: 2, Page: 266-277
1968
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Four normal lactating glands of Mice and nine mammary cancers have been studied by quantitative electron microscopy. Normal lactating cells are characterized by a high organelle development: the mitochondria occupy 11.2% and the Golgi apparatus 7.4% of the cytoplasm (without lipid droplets). The ergastoplasm attains a surface of 4.7 square micron per cubic micron of cytoplasm. All mammary cancers examined had a lower organelle development than normal lactating gland cells and this independently from the fact whether the tumour cells were secreting or not. A relationship between the number of virus particles in the section area and the degree of organelle development does not exist. © 1968 Springer-Verlag.

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