Ultrastructural study of the childhood mitochondrial myopathic syndrome associated with lactic acidosis
European Journal of Pediatrics, ISSN: 0340-6199, Vol: 139, Issue: 1, Page: 25-30
1982
- 44Citations
- 2Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations44
- Citation Indexes44
- 44
- CrossRef37
- Captures2
- Readers2
Article Description
The quadriceps femoris muscle and the muscularis mucosae of the rectum from two children with mitochondrial myopathic syndrome associated with lactic acidosis were studied by electron microscopy. Striking morphological abnormalities of mitochondria were noted not only in the skeletal but also in the smooth muscle cells. Endothelial cells of blood capillaries distributed in these affected muscles were so greatly swollen that the capillary lumen was almost occluded. In contrast, surface epithelial and glandular epithelial cells of the rectum contained normal mitochondria, and fenestrated capillaries in the propria mucosae remained intact. Long-term ischemia resulting from occlusive changes of the capillary wall may be responsible for the mitochondrial alterations of muscle cells. © 1982 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0019969786&origin=inward; http://dx.doi.org/10.1007/bf00442074; http://www.ncbi.nlm.nih.gov/pubmed/7173254; http://link.springer.com/10.1007/BF00442074; http://www.springerlink.com/index/pdf/10.1007/BF00442074; https://dx.doi.org/10.1007/bf00442074; https://link.springer.com/article/10.1007/BF00442074; http://www.springerlink.com/index/10.1007/BF00442074
Springer Nature
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