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Immediate hypersensitivity to ovalbumin in children with hen's egg white allergy

European Journal of Pediatrics, ISSN: 0340-6199, Vol: 147, Issue: 6, Page: 606-608
1988
  • 20
    Citations
  • 0
    Usage
  • 6
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    20
    • Citation Indexes
      20
  • Captures
    6

Article Description

Serum concentration of IgE, IgG and IgG antibodies to ovalbumin and basophil sensitivity to ovalbumin were compared with the results of a titrated oral provocation test with ovalbumin in 27 children sensitive to hen's egg white, of whom 17 responded with an immediate hypersensitivity reaction. Neither the serum level of IgE, IgG and IgG antibodies to ovalbumin nor a positive histamine release test predicted the clinical relevance of ovalbumin sensitivity. The children with a positive challenge test had a significantly higher IgE/IgE ratio and tended to be younger and to have higher serum IgE levels and a higher IgG/IgG ratio than those with a negative challenge test. We conclude that an oral provocation test is necessary to confirm the diagnosis of food allergy. © 1988 Springer-Verlag.

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