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Über die Natur der im Epicutantest wirksamen Stoffe von Staphylococcus aureus - V. Biochemische Untersuchung der Ultrafiltrationsfraktionen

Archiv fur klinische und experimentelle Dermatologie, ISSN: 0300-8614, Vol: 230, Issue: 4, Page: 402-412
1967
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  • Citations
    3
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      3

Article Description

The investigation of the eczematogenic ultrafiltrate (IIIa) of cellophane-culture filtrate from staphylococci showed the lack of activities of hemolysins, coagulase, lethalfactor and other toxins. No precipitating antibodies against IIIa could be produced in rabbits. Fraction IIIa provoked an intracutaneous reaction of the immediate type in man but not of the delayed type which was caused by the highmolecular fraction IIIb. Intracutaneous tests in guinea pigs showed corresponding results, but fraction IIIa in this case did not cause a reaction of immediate type. Attempts to isolate the eczematogenic substances of fraction IIIa did not yield satisfying results when paperchromatography, paperelectrophoresis and continuous electrophoresis were used. © 1967 Springer-Verlag.

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