Cutaneous sensitivity to ultraviolett light and chemical irritants
Archives of Dermatological Research, ISSN: 0340-3696, Vol: 272, Issue: 3-4, Page: 269-278
1982
- 49Citations
- 8Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Article Description
This investigation examines the relationship between the sun sensitivity of human skin and its response to chemical irritants. Forty-four Caucasoid subjects with normal back skin were studied. The minimal erythema dose (MED) was determined with the sunburning spectrum of a high-pressure mercury lamp. Cutaneous irritability was quantified using a series of seven irritants of different chemical structure, solubility, and concentrations. The response was either expressed as a threshold value of exposure time (ammonium hydroxide, sodium hydroxide) or was graded after a standard exposure in intensity of whealing (dimethyl sulphoxide) or erythema (sodium lauryl sulphate, quaternium 1, croton oil, kerosene). A significant correlation between the MED and the response to all seven primary irritants was found. The relationship was better for water-soluble irritants than for lipid-soluble ones. Despite marked individual variations the determination of the MED is suggested as a valuable tool in identifying hyperirritable skin. Skin typing based on complexion and sunburn history proved to be less reliable. © 1982 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0020080696&origin=inward; http://dx.doi.org/10.1007/bf00509056; http://www.ncbi.nlm.nih.gov/pubmed/7165336; http://link.springer.com/10.1007/BF00509056; http://www.springerlink.com/index/pdf/10.1007/BF00509056; https://dx.doi.org/10.1007/bf00509056; https://link.springer.com/article/10.1007/BF00509056; http://www.springerlink.com/index/10.1007/BF00509056
Springer Nature
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