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Biosynthesis of collagen and elastin by chick embryo skin during maturation

Archiv für Dermatologische Forschung, ISSN: 0340-3696, Vol: 249, Issue: 2, Page: 99-104
1974
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Article Description

The biosynthess of collagen and elastin by chick embryo skin of 11-16 days of development was studied. An increased uptake of (C) proline and (C) lysine on day 12 was observed in collagen peptides and in elastin extracted from the skin samples. (C)hydroxyproline followed the same pattern as the uptake of its precursor into the collagenase-digested peptide fraction. The conversion of (C)lysine into (C)hydroxylysine was low. The conversion of (C)glutamic acid and (C)glutamine into (C)proline and (C)hydroxyproline by the skin of chicken embryos may be an important pathway. As far as (C)proline and (C)lysine is concerned elastin showed a similar pattern of changes during the maturation process. © 1974 Springer-Verlag.

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