Renal test dyes IV - Intravital fluorescence microscopy and microphotometry of the tubularly secreted dye sulfonefluorescein
Pflügers Archiv European Journal of Physiology, ISSN: 0031-6768, Vol: 364, Issue: 1, Page: 83-89
1976
- 15Citations
- 2Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations15
- Citation Indexes15
- 15
- CrossRef9
- Captures2
- Readers2
Article Description
The present study describes for the first time the use of the fluorescent dye sulfonefluorescein for intravital microscopy and microphotometry on the renal surface of rats. With help of this dye tubular secretion can be observed in mammalian kidney in vivo. Tubular secretion can further be quantified with microphotometrical measurements. The molecular structure of sulfonefluorescein is closely related to phenol red, which is known for its tubular secretion. Clearance experiments also show a secretion of sulfonefluorescein. The secretion can be inhibited by probenecid. Ureter ligation causes a strong increase in tubular concentration of the dye. After a temporary ischemia dye accumulation in tubular lumen is greatly reduced. © 1976 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0017079211&origin=inward; http://dx.doi.org/10.1007/bf01062916; http://www.ncbi.nlm.nih.gov/pubmed/986619; http://link.springer.com/10.1007/BF01062916; http://www.springerlink.com/index/pdf/10.1007/BF01062916; http://www.springerlink.com/index/10.1007/BF01062916; https://dx.doi.org/10.1007/bf01062916; https://link.springer.com/article/10.1007/BF01062916
Springer Science and Business Media LLC
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