PlumX Metrics
Embed PlumX Metrics

Cajal-Retzius neurons in developing monkey neocortex show immunoreactivity for calcium binding proteins

Journal of Neurocytology, ISSN: 0300-4864, Vol: 19, Issue: 2, Page: 200-212
1990
  • 88
    Citations
  • 0
    Usage
  • 29
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

Immunoreactivity for two calcium binding proteins, 28 kDa calbindin and parvalbumin, was used to label cells morphologically identical to Cajal-Retzius neurons in the developing visual, prefrontal, sensory-motor and temporal cortex of Old World monkeys. At all fetal ages examined (E110-E155), Cajal-Retzius neurons throughout the cortex were immunoreactive for calbindin as well as being acetylcholinesterase positive. Between E130 and E150, the calbindin-immunoreactive Cajal-Retzius cells in the visual cortex, and a few in other cortical areas, also showed parvalbumin immunoreactivity. A reduced population of immunoreactive Cajal-Retzius cells was detected at birth, and none could be visualized by immunocytochemistry or histochemistry at later postnatal ages. Calbindin and parvalbumin immunoreactivity represents a potentially useful marker for this developmentally regulated population of neurons, and the varied expression of the two proteins suggests that Cajal-Retzius neurons may represent a neurochemically heterogeneous cell population. © 1990 Chapman and Hall Ltd.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know