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Thiopyronine and 8-methoxypsoralen sensitized photodynamic effect on DNA synthesis in yeast

Radiation and Environmental Biophysics, ISSN: 0301-634X, Vol: 24, Issue: 2, Page: 157-160
1985
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The synthesis of DNA in growing yeast cells was investigated after photodynamic treatment of the cells with thiopyronine (TP) and visible light or with 8-methoxypsoralen (8-MOP) and UVA light. DNA synthesis was inhibited after photodynamic treatment with 8-MOP but not after photodynamic treatment with TP. This result is further evidence that the photodynamic effect with TP does not attack nuclear DNA in eucaryotic cells. © 1985 Springer-Verlag.

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