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Licht- und elektronenmikroskopische Betrachtungen an operativ entfernten thorakalen Ganglien des menschlichen Grenzstrangs

Acta Neurovegetativa, ISSN: 0300-9564, Vol: 30, Issue: 1-4, Page: 464-495
1967
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By thoracoscopic technique developed by Kux and Wittmoser, thoracic sympathetic ganglia were exstirpated from patients suffering from asthma bronchiale, ulcus ventriculi et duodeni, hyperhidrosis and Raynaud's disease and examined by light and electron microscopy. The ganglionic cells showed degeneration and regeneration in nucleus, perikaryon, nerve fibres and satellite cells. Light microscopy reveals among other abnormalities vacuolation, granular structure, pyknosis, karyorhexis, polynucleosis, hypertrophy and hyperplasia of the neurites and dendritic fibres. Electron micrographs disclose bizarre contours of the deformed nucleus. Concurrently with condensations of the karyoplasm and cytoplasm, dilated cavities of the endoplasmic reticulum and swollen mitochondria are to be noted. Some ganglionic cells show, in contrast to these regressive changes, a considerable proliferation of their mitochondria. Alterations of the myelin sheaths and diminuation of the neurotubuli can be observed besides of other changes. The electron microscopic observations are only mild inspite of the striking findings of the light microscopy. © 1967 Springer-Verlag.

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