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Modulation of SERCA2 activity: Regulated splicing and interaction with phospholamban

Bioscience Reports, ISSN: 0144-8463, Vol: 15, Issue: 5, Page: 307-315
1995
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Review Description

Ca-uptake into intracellular stores is mediated by the sarco/endoplasmic reticulum CaATPases (SERCAs). This review deals first with the gene structural and the characterization of the tissue-specific SERCA2 transcript processing. Secondly, the two different protein isoforms and their regulation are described. Finally, this review ends with a discussion on the possible physiological role of the SERCA2 isoform diversity. © 1995 Plenum Publishing Corporation.

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