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Circadian rhythm of apical Na-channels and Na-transport in rabbit distal colon

Experientia, ISSN: 0014-4754, Vol: 44, Issue: 7, Page: 608-610
1988
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In vivo and in vitro studies showed that electrogenic sodium transport in rabbit distal colon is modulated by aldosterone. It varies in a circadian rhythm; the external synchronizer is the light-dark cycle. The site of regulation was found to be in the apical membrane of colonic epithelial cells, in which the number of conducting sodium-channels is increased by aldosterone. © 1988 Birkhäuser Verlag.

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