Administration of leu-enkephalin impairs the acquisition of preference for ethanol
Psychopharmacology, ISSN: 0033-3158, Vol: 100, Issue: 3, Page: 350-354
1990
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Article Description
The effects of subcutaneous administration of leuenkephalin (LEU-E) (10, 100 and 300 μg/kg) and LEU-E (100 μg/kg) plus naloxone (2.5 mg/kg) on ethanol preference and fluid intake have been investigated in rats. Under our procedural conditions, rats develop ethanol preference through forced ethanol drinking (conditioning session). Preconditioning administration of LEU-E induced a reduction of later ethanol preference. Post-conditioning administration of LEU-E (10 and 100 μg/kg) also attenuated the development of ethanol preference. NX antagonized the effects of LEU-E on ethanol preference and fluid consumption in the two experimental procedures used, indicating an involvement of opioid receptors in the LEU-E-induced impairment of the acquisition of ethanol preference. © 1990 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0025021895&origin=inward; http://dx.doi.org/10.1007/bf02244605; http://www.ncbi.nlm.nih.gov/pubmed/2315432; http://link.springer.com/10.1007/BF02244605; http://www.springerlink.com/index/pdf/10.1007/BF02244605; http://www.springerlink.com/index/10.1007/BF02244605; https://dx.doi.org/10.1007/bf02244605; https://link.springer.com/article/10.1007/BF02244605
Springer Nature
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