Acute immobilization stress reduces (±DOI)-induced 5-HT receptor-mediated head shakes in rats
Psychopharmacology, ISSN: 0033-3158, Vol: 119, Issue: 1, Page: 9-14
1995
- 31Citations
- 15Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations31
- Citation Indexes31
- 31
- CrossRef22
- Captures15
- Readers15
- 15
Article Description
Acute immobilization stress induced by taping four limbs, applying tail pinch stress and electric foot shock stress immediately reduced the frequency of head shakes induced by 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane ((±)DOI), a 5-HT agonist in rats. Immobilization stress due to the use of cylinder restraint and forced swimming did not affect 5-HT-mediated behavior. Acute immobilization stress did not affect [H]ketanserin binding to the 5HT receptor in the prefrontal cortex and hippocampus. Presynaptic serotonergic lesions with 5,7-dihydroxytryptamine (5,7-DHT) did not affect the reduction in 5-HT-mediated behavior after acute immobilization stress. The decreases in head shake frequency after acute immobilization stress by taping were attenuated by pretreatment with diazepam (2.5 mg/kg IP): This attenuation was reversed by pretreatment with flumazenil (10 mg/kg IP). The reduction in (±)DOI- induced 5-HT-mediated behavior caused by stress may be related to a change in agonist affinity to the receptor or changes in other neurotransmitter systems or the effect of PI turnover. © 1995 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0029034961&origin=inward; http://dx.doi.org/10.1007/bf02246047; http://www.ncbi.nlm.nih.gov/pubmed/7675955; http://link.springer.com/10.1007/BF02246047; http://www.springerlink.com/index/pdf/10.1007/BF02246047; http://www.springerlink.com/index/10.1007/BF02246047; https://dx.doi.org/10.1007/bf02246047; https://link.springer.com/article/10.1007/BF02246047
Springer Science and Business Media LLC
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