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The effect of prophylaxis for thrombosis on heterotopic ossification following total hip joint replacement

Archives of Orthopaedic and Traumatic Surgery, ISSN: 0344-8444, Vol: 102, Issue: 2, Page: 114-117
1983
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The effect of prophylaxis for thrombosis on heterotopic ossification was investigated using 216 total hip joint endoprostheses implanted between 1976 and 1978. During this period a random comparative study of low dose heparin and oxyphenbutazone / acetylsalycilic acid was carried out. The rate of ossification in the 216 hip joints was 17.6%, and was about average for the values specified in literature on this subject. Heterotopic ossification occurred in 30.1% of the 103 hip joints treated with heparin, whilst the rate of ossification in the 113 hip joints treated with oxyphenbutazone / acetylsalycilic acid was only 6.2%. This represents a statistically significant difference in disfavour of prophylaxis with heparin. © 1983 Springer-Verlag.

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