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Application of nuclear analytical methods in the investigation and identification of new selenoproteins

Biological Trace Element Research, ISSN: 1559-0720, Vol: 43, Issue: 1, Page: 287-297
1994
  • 30
    Citations
  • 0
    Usage
  • 7
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    30
    • Citation Indexes
      30
  • Captures
    7

Article Description

Nuclear methods have been applied in the investigation of selenium-containing proteins in rat tissues. Selenium was determined in tissues, cells, and cellular compartments by instrumental neutron activation analysis viaSe orSe. For tracer studies, the selenium compounds were labeled in vivo by administeringSe with a high specific activity to rats. Quantitative determination of very small amounts of the element in protein fractions was achieved by measurement of the tracer after replenishment of selenium-depleted animals with the labeled element. The application of the nuclear methods in the detection, characterization, and identification of new selenium-containing proteins is shown with the help of some examples. © 1994, Humana Press Inc.. All rights reserved.

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