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Vascular changes of pancreatic ducts and vessels in acute necrotizing, and in chronic pancreatitis in humans

International Journal of Pancreatology, ISSN: 1537-3649, Vol: 8, Issue: 1, Page: 13-22
1991
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Article Description

Five patients with severe acute pancreatitis (AP) underwent subtotal pancreatectomy, and six patients with advanced chronic pancreatitis (CP) were subjected to pancreatic resection. Microangiography and histological studies were performed on the resected pancreata. All patients with AP had histologically verified necrotizing pancreatitis. Pancreatic ducts in the necrotic areas had severe inflammation in their walls and a decrease in their vascularity. The ductal walls of CP patients were indistinguishable from the surrounding fibrosis and the vascular supply of the ducts was markedly diminished. The vessels were reduced in number, and their calibers varied considerably. Ductal ischemia in connection with AP and CP is discussed. © 1991 Humana Press Inc.

Bibliographic Details

Pekka Pítkäranta; Leena Kivisaari; Stig Nordling; Pekka Nuutinen; Torn Schröder

Springer Science and Business Media LLC

Medicine; Biochemistry, Genetics and Molecular Biology

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