Aromatic sulfonyl hydrazides and sulfonyl hydrazones: Antimicrobial activity and physical properties
Medicinal Chemistry Research, ISSN: 1054-2523, Vol: 22, Issue: 3, Page: 1330-1338
2013
- 27Citations
- 23Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
A series of novel aromatic sulfonamide derivatives (1-7) were synthesized and characterized by elemental analyses, FT-IR, H NMR, C NMR, and LC/MS techniques. The compounds' quantum mechanical descriptors, surface area, and molecular volume were calculated. All the synthesized compounds were evaluated in vitro as antimicrobial agents against representative strains of gram-positive and gram-negative bacteria and as antifungal agents for yeast by both the disc diffusion and minimal inhibition concentration methods for comparison. All the bacteria and fungi studied were screened against some commercial antibiotics to compare with our chemicals' zone diameters. Quantitative structure-activity relationship studies with multiple linear regression analysis were applied to find the correlation between the different calculated molecular descriptors of the synthesized compounds and biological activity. Graphical Abstract: [Figure not available: see fulltext.] © 2012 Springer Science+Business Media, LLC.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84874110691&origin=inward; http://dx.doi.org/10.1007/s00044-012-0104-0; http://link.springer.com/10.1007/s00044-012-0104-0; http://link.springer.com/content/pdf/10.1007/s00044-012-0104-0; http://link.springer.com/content/pdf/10.1007/s00044-012-0104-0.pdf; http://link.springer.com/article/10.1007/s00044-012-0104-0/fulltext.html; https://dx.doi.org/10.1007/s00044-012-0104-0; https://link.springer.com/article/10.1007/s00044-012-0104-0
Springer Science and Business Media LLC
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