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Targeting CSPG4 for isolation of melanoma cell-derived exosomes from body fluids

HNO, ISSN: 1433-0458, Vol: 68, Issue: 2, Page: 100-105
2020
  • 15
    Citations
  • 0
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  • 38
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  • 0
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Metric Options:   Counts1 Year3 Year

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Review Description

This manuscript describes the functional properties of the exosomes released from melanoma cells. It details the characteristics of the tumor antigen chondroitin sulfate proteoglycan 4 (CSPG4), which is used as a marker to separate exosomes released by melanoma cells from exosomes released by nonmalignant cells. The results are discussed in view of the potential role of melanoma cell-derived exosomes in the escape of malignant cells from the host’s immune system.

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