Functional roles of E3 ubiquitin ligases in prostate cancer
Journal of Molecular Medicine, ISSN: 1432-1440, Vol: 100, Issue: 8, Page: 1125-1144
2022
- 9Citations
- 8Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations9
- Citation Indexes9
- Captures8
- Readers8
Review Description
Prostate cancer (PCa) is a malignant epithelial tumor of the prostate gland with a high male cancer incidence. Numerous studies indicate that abnormal function of ubiquitin–proteasome system (UPS) is associated with the progression and metastasis of PCa. E3 ubiquitin ligases, key components of UPS, determine the specificity of substrates, and substantial advances of E3 ubiquitin ligases have been reached recently. Herein, we introduce the structures and functions of E3 ubiquitin ligases and summarize the mechanisms of E3 ubiquitin ligases-related PCa signaling pathways. In addition, some progresses in the development of inhibitors targeting E3 ubiquitin ligases are also included.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85133877971&origin=inward; http://dx.doi.org/10.1007/s00109-022-02229-9; http://www.ncbi.nlm.nih.gov/pubmed/35816219; https://link.springer.com/10.1007/s00109-022-02229-9; https://dx.doi.org/10.1007/s00109-022-02229-9; https://link.springer.com/article/10.1007/s00109-022-02229-9
Springer Science and Business Media LLC
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