Theoretical and computational studies of vectorial processes in biomolecular systems
Theoretical Chemistry Accounts, ISSN: 1432-881X, Vol: 116, Issue: 1-3, Page: 51-59
2006
- 13Citations
- 16Captures
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Article Description
Efficient vectorial processes such as the transduction of bioenergy and signals are characteristics that strikingly distinguish living systems from inanimate materials. Recent developments in biophysical and biochemical techniques have provided new information about the structure, dynamics and interaction of biomolecules involved in vectorial life processes at multiple length and temporal scales. This wealth of data makes it possible to carry out theoretical and computational studied of key mechanistic questions associated with complex life processes at an unprecedented level. Using two "vectorial biomolecular machines", myosin and cytochrome c oxidase, as examples, we discuss the identification of interesting and biologically relevant questions that require thorough theoretical analysis. Technical challenges and recent progress related to these theoretical investigations are briefly summarized.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33748253522&origin=inward; http://dx.doi.org/10.1007/s00214-005-0022-z; http://link.springer.com/10.1007/s00214-005-0022-z; http://link.springer.com/content/pdf/10.1007/s00214-005-0022-z; http://link.springer.com/content/pdf/10.1007/s00214-005-0022-z.pdf; http://link.springer.com/article/10.1007/s00214-005-0022-z/fulltext.html; http://www.springerlink.com/index/10.1007/s00214-005-0022-z; http://www.springerlink.com/index/pdf/10.1007/s00214-005-0022-z; https://dx.doi.org/10.1007/s00214-005-0022-z; https://link.springer.com/article/10.1007/s00214-005-0022-z
Springer Science and Business Media LLC
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