Diazepam-induced changes of optokinetic nystagmus fast phase.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, ISSN: 0014-4819, Vol: 167, Issue: 3, Page: 446-450
2005
- 4Citations
- 12Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations4
- Citation Indexes4
- CrossRef2
- Captures12
- Readers12
- 12
Article Description
Since specific benzodiazepine (Bz) binding sites have been found in the vision and oculomotor control areas of the central nervous system (CNS), the fast phases of optokinetic nystagmus (OKN) should be affected by Bz administration. In this study, we examine the effects of Bzs on OKN fast phases under closed- and open-loop experimental conditions. Six normal subjects participated in the experiments. The eye movements were measured by the magnetic field, search coil technique, 90 min after diazepam or placebo administration. The study was performed in a randomized, double-blind fashion. After diazepam, the mean amplitude (MAmp) and mean peak velocity (MVel) of OKN fast phases decreased significantly under both experimental conditions. The percentage decreases in MAmp and MVel under the open-loop condition were significantly larger than those under the closed-loop condition. The results indicate that the fast phases of OKN could sensitively reflect the pharmacodynamic effects of Bzs on the CNS.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33645242049&origin=inward; http://dx.doi.org/10.1007/s00221-005-0176-x; http://www.ncbi.nlm.nih.gov/pubmed/16283404; http://link.springer.com/10.1007/s00221-005-0176-x; https://dx.doi.org/10.1007/s00221-005-0176-x; https://link.springer.com/article/10.1007/s00221-005-0176-x; http://www.springerlink.com/index/10.1007/s00221-005-0176-x; http://www.springerlink.com/index/pdf/10.1007/s00221-005-0176-x
Springer Science and Business Media LLC
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know