ULBP4/RAET1E is highly polymorphic in the Old World monkey
Immunogenetics, ISSN: 0093-7711, Vol: 63, Issue: 8, Page: 501-509
2011
- 7Citations
- 10Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations7
- Citation Indexes7
- CrossRef6
- Captures10
- Readers10
- 10
Article Description
Natural-killer group 2 member D (NKG2D) is an activating receptor that plays an important role in the immune response mediated by NK cells, γδ T cells, and CD8 T cells. In humans, MHC class I chain-related genes and UL-16 binding protein (ULBP)/retinoic acid early transcript 1 (REAT1) gene family encode ligands for NKG2D. The rhesus and crab-eating macaques, which belong to the Old World monkeys, are widely used as non-human primate models in medical researches on the immunological process. In the present study, we investigated the polymorphisms of ULBP4/RAET1E, a member of the ULBP/RAET1 family, and found 25 and 14 alleles from the rhesus and crab-eating macaques, respectively, of which diversities were far more extended than in humans. A phylogenetic study suggested that the allelic diversification of ULBP4/RAET1E predated the divergence of rhesus and crab-eating macaques. © 2011 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79961032288&origin=inward; http://dx.doi.org/10.1007/s00251-011-0531-y; http://www.ncbi.nlm.nih.gov/pubmed/21553130; http://link.springer.com/10.1007/s00251-011-0531-y; https://dx.doi.org/10.1007/s00251-011-0531-y; https://link.springer.com/article/10.1007/s00251-011-0531-y; http://www.springerlink.com/index/10.1007/s00251-011-0531-y; http://www.springerlink.com/index/pdf/10.1007/s00251-011-0531-y
Springer Science and Business Media LLC
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