Hypodense regions in unenhanced CT identify nonviable myocardium: Validation versus 18F-FDG PET
European Journal of Nuclear Medicine and Molecular Imaging, ISSN: 1619-7070, Vol: 39, Issue: 12, Page: 1920-1926
2012
- 6Citations
- 20Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations6
- Citation Indexes6
- CrossRef3
- Captures20
- Readers20
- 20
Article Description
Purpose: The aim of the present study was to evaluate the accuracy of hypodense regions in non-contrast-enhanced cardiac computed tomography (unenhanced CT) to identify nonviable myocardial scar tissue. Methods: Hypodense areas were visually identified in unenhanced CT of 80 patients in the left ventricular anterior, apical, septal, lateral and inferior myocardium and CT density was measured in Hounsfield units (HU). Findings were compared to 18F-fluorodeoxyglucose uptake by positron emission tomography (FDG PET), which served as the standard of reference to distinguish scar ( <50 % FDG uptake) from viable tissue (≥50 % uptake). Results: Visually detected hypodense regions demonstrated a sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 74, 97, 84 and 94 %, respectively. A receiver-operating characteristic (ROC) curve analysis revealed a cutoff value of mean HU at<28.8 for predicting scar tissue with an area under the curve of 0.93 yielding a sensitivity, specificity, PPV and NPV of 94, 90, 67 and 99 %, respectively. Conclusion: Hypodense regions in unenhanced cardiac CT scans allow accurate identification of nonviable myocardial scar tissue. © Springer-Verlag 2012.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84869097154&origin=inward; http://dx.doi.org/10.1007/s00259-012-2212-y; http://www.ncbi.nlm.nih.gov/pubmed/22926710; http://link.springer.com/10.1007/s00259-012-2212-y; https://dx.doi.org/10.1007/s00259-012-2212-y; https://link.springer.com/article/10.1007/s00259-012-2212-y; http://www.springerlink.com/index/10.1007/s00259-012-2212-y; http://www.springerlink.com/index/pdf/10.1007/s00259-012-2212-y
Springer Science and Business Media LLC
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