Effectiveness and Role of Using Hyaluronic Acid Injections for Gluteal Augmentation: A Comprehensive Systematic Review of Techniques and Outcomes

Abstract: We have reviewed the article “Effectiveness and Role of Using Hyaluronic Acid Injections for Gluteal Augmentation: A Comprehensive Systematic Review of Techniques and Outcomes” by Mortada et al. in Aesthetic Plastic Surgery with keen interest. This study aims to comprehensively assess the effectiveness and role of hyaluronic acid (HA) in gluteal augmentation. However, we raise concerns about the methodologies employed in the reviewed studies. For effective treatments, understanding the properties of the active substance is essential for standardization. Thoroughly grasping the key characteristics of the employed HAs is vital to identify correlations between these properties, outcomes, and complication risks. Understanding HA’s rheological properties, including viscosity, elasticity, and cohesiveness, is pivotal for selecting appropriate dermal fillers for the gluteal region. Another significant aspect of HA use is cohesiveness, arising from internal adhesion based on HA concentration and cross-linking. This cohesiveness resists vertical forces upon implantation, influencing tissue lifting and projection. Gel texture, influenced by Cross-Linking Degree, Particle Size, Molecular Weight, and HA Concentration, also plays a crucial role. While acknowledging authors’ contributions, further analysis should consider these factors. Level of Evidence V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.