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A systematic review of high-fibre dietary therapy in diverticular disease

International Journal of Colorectal Disease, ISSN: 0179-1958, Vol: 27, Issue: 4, Page: 419-427
2012
  • 97
    Citations
  • 0
    Usage
  • 148
    Captures
  • 3
    Mentions
  • 16
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    97
    • Citation Indexes
      93
    • Policy Citations
      3
      • Policy Citation
        3
    • Clinical Citations
      1
      • PubMed Guidelines
        1
  • Captures
    148
  • Mentions
    3
    • News Mentions
      2
      • News
        2
    • References
      1
      • Wikipedia
        1
  • Social Media
    16
    • Shares, Likes & Comments
      16
      • Facebook
        16

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Review Description

Purpose The exact pathogenesis of diverticular disease of the sigmoid colon is not well established. However, the hypothesis that a low-fibre diet may result in diverticulosis and a high-fibre diet will prevent symptoms or complications of diverticular disease is widely accepted. The aim of this review is to assess whether a high-fibre diet can improve symptoms and/or prevent complications of diverticular disease of the sigmoid colon and/or prevent recurrent diverticulitis after a primary episode. Methods Clinical studies were eligible for inclusion if they assessed the treatment of diverticular disease or the prevention of recurrent diverticulitis with a high-fibre diet. The following exclusion criteria were used for study selection: studies without comparison of the patient group with a control group. Results No studies concerning prevention of recurrent diver-ticulitis with a high-fibre diet met our inclusion criteria. Three randomised controlled trials (RCT) and one case-control study were included in this systematic review. One RCT of moderate quality showed no difference in the primary endpoints. A second RCT of moderate quality and the case- control study found a significant difference in favour of a high-fibre diet in the treatment of symptomatic diverticular disease. The third RCTof moderate quality found a significant difference in favour of methylcellulose (fibre supplement). This study also showed a placebo effect. Conclusion High-quality evidence for a high-fibre diet in the treatment of diverticular disease is lacking, and most recommendations are based on inconsistent level 2 and mostly level 3 evidence. Nevertheless, high-fibre diet is still recommended in several guidelines. © 2011 CARS.

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