A systematic review of high-fibre dietary therapy in diverticular disease
International Journal of Colorectal Disease, ISSN: 0179-1958, Vol: 27, Issue: 4, Page: 419-427
2012
- 97Citations
- 148Captures
- 3Mentions
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Metrics Details
- Citations97
- Citation Indexes93
- 93
- CrossRef60
- Policy Citations3
- Policy Citation3
- Clinical Citations1
- PubMed Guidelines1
- Captures148
- Readers148
- 148
- Mentions3
- News Mentions2
- News2
- References1
- Wikipedia1
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Review Description
Purpose The exact pathogenesis of diverticular disease of the sigmoid colon is not well established. However, the hypothesis that a low-fibre diet may result in diverticulosis and a high-fibre diet will prevent symptoms or complications of diverticular disease is widely accepted. The aim of this review is to assess whether a high-fibre diet can improve symptoms and/or prevent complications of diverticular disease of the sigmoid colon and/or prevent recurrent diverticulitis after a primary episode. Methods Clinical studies were eligible for inclusion if they assessed the treatment of diverticular disease or the prevention of recurrent diverticulitis with a high-fibre diet. The following exclusion criteria were used for study selection: studies without comparison of the patient group with a control group. Results No studies concerning prevention of recurrent diver-ticulitis with a high-fibre diet met our inclusion criteria. Three randomised controlled trials (RCT) and one case-control study were included in this systematic review. One RCT of moderate quality showed no difference in the primary endpoints. A second RCT of moderate quality and the case- control study found a significant difference in favour of a high-fibre diet in the treatment of symptomatic diverticular disease. The third RCTof moderate quality found a significant difference in favour of methylcellulose (fibre supplement). This study also showed a placebo effect. Conclusion High-quality evidence for a high-fibre diet in the treatment of diverticular disease is lacking, and most recommendations are based on inconsistent level 2 and mostly level 3 evidence. Nevertheless, high-fibre diet is still recommended in several guidelines. © 2011 CARS.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84862997699&origin=inward; http://dx.doi.org/10.1007/s00384-011-1308-3; http://www.ncbi.nlm.nih.gov/pubmed/21922199; http://link.springer.com/10.1007/s00384-011-1308-3; http://www.springerlink.com/index/10.1007/s00384-011-1308-3; http://www.springerlink.com/index/pdf/10.1007/s00384-011-1308-3; https://dx.doi.org/10.1007/s00384-011-1308-3; https://link.springer.com/article/10.1007/s00384-011-1308-3
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