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Systematic screening for occupations and occupational exposures in head and neck squamous cell carcinoma patients

European Archives of Oto-Rhino-Laryngology, ISSN: 1434-4726, Vol: 276, Issue: 3, Page: 857-864
2019
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Article Description

Purpose: The importance of occupational exposures in patients with head and neck squamous cell carcinomas (HNSCC) has received little attention. Methods: In a single-center study, we prospectively characterized occupational exposures in 154 HNSCC cancer patients in a systematic occupational consultation and examined the association between most frequent exposures, HNSCC stage and localization. Results: Patients occupied a mean of 3.3 different positions during their working life. The prevalence of asbestos, the most frequent exposure (46 patients; 29.9%) was higher than in the French population > 50 years. Other frequent exposures were solvents (n = 26; 16.9%) and silica (n = 19; 12.3%). For 37 patients (24%) a possible link was identified between occupational exposures and HNSCC. Duration of asbestos exposure was significantly higher (p = 0.04) in patients with hypopharyngeal and laryngeal cancer compared to other localizations. Conclusions: Occupational exposures are frequent in patients with HNSCC and should receive increased attention by physicians.

Bibliographic Details

Deneuve, Sophie; Charbotel, Barbara; Massardier-Pilonchéry, Amélie; Fort, Emmanuel; Milliet-Baude, Charlotte; Pérol, Olivia; Fayette, Jérome; Zrounba, Philippe; Fervers, Béatrice

Springer Science and Business Media LLC

Medicine

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