Low level of IGF-1 in obesity may be related to obstructive sleep apnea syndrome
Lung, ISSN: 0341-2040, Vol: 185, Issue: 5, Page: 309-314
2007
- 36Citations
- 32Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations36
- Citation Indexes36
- 36
- CrossRef25
- Captures32
- Readers32
- 32
Article Description
The aim of this study was to compare serum insulin-like growth factor (IGF-1) levels in patients with obstructive sleep apnea syndrome (OSAS) with those of nonapneic controls and to determine the risk factors of low IGF-1 levels in patients with OSAS. The study included 39 newly diagnosed moderate-to-severe OSAS patients and 36 nonapneic controls. Overnight polysomnography (PSG) was performed in all patients. The circulating levels of IGF-1 in the OSAS group were significantly lower than those of the control group (p < 0.05). There was a significant negative correlation between IGF-1 and logarithmic transformation (Ln) of the apnea-hypopnea index (AHI), duration of apnea-hypopnea, arousal index, average desaturation, and oxygen desaturation index (ODI). The result of stepwise regression analyses showed that OSAS (p = 0.001) was a risk factor for a low IGF-1 level, independent of age, gender, and body mass index (BMI). Our findings demonstrated that there was a significant negative correlation between IGF-1 and Ln AHI and that OSAS reduced the circulating levels of IGF-1. © 2007 Springer Science+Business Media, LLC.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=34548577002&origin=inward; http://dx.doi.org/10.1007/s00408-007-9026-x; http://www.ncbi.nlm.nih.gov/pubmed/17721831; https://link.springer.com/10.1007/s00408-007-9026-x; http://www.springerlink.com/index/10.1007/s00408-007-9026-x; http://www.springerlink.com/index/pdf/10.1007/s00408-007-9026-x; https://dx.doi.org/10.1007/s00408-007-9026-x; https://link.springer.com/article/10.1007/s00408-007-9026-x
Springer Science and Business Media LLC
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