CXCL11 is involved in leucocyte recruitment to the central nervous system in neuroborreliosis
Journal of Neurology, ISSN: 0340-5354, Vol: 252, Issue: 7, Page: 820-823
2005
- 26Citations
- 15Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations26
- Citation Indexes26
- 26
- CrossRef20
- Captures15
- Readers15
- 15
Article Description
We investigated the role of the CXCR3 chemokine CXCL11 (I-TAC) for leukocyte recruitment to the CSF in neuroborreliosis (NB). CXCL11 levels in the CSF of 17 patients with acute NB were elevated compared with 20 non-inflammatory controls (100.1 vs. 54.1pg/ml, p = 0.002). Using a modified Boyden chamber chemotaxis-assay, the CSF of patients with acute NB was more chemotactic than the control CSF-samples (p = 0.001). A strong correlation (p < 0.001) between CXCL11 levels, chemotactic activity and CSF-white cell count was detected. Though the chemotactic activity of CSF from NB patients was only partially reduced by a human recombinant CXCL11 antibody, these findings suggest that, among other chemotactic factors, CXCL11 may play a role in the chemotaxis of mononuclear cells in NB.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=22144480900&origin=inward; http://dx.doi.org/10.1007/s00415-005-0752-9; http://www.ncbi.nlm.nih.gov/pubmed/15750703; http://link.springer.com/10.1007/s00415-005-0752-9; https://dx.doi.org/10.1007/s00415-005-0752-9; https://link.springer.com/article/10.1007/s00415-005-0752-9; http://www.springerlink.com/index/10.1007/s00415-005-0752-9; http://www.springerlink.com/index/pdf/10.1007/s00415-005-0752-9
Springer Science and Business Media LLC
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