Drosophila Jing is part of the Breathless fibroblast growth factor receptor positive feedback loop
Development Genes and Evolution, ISSN: 0949-944X, Vol: 220, Issue: 7-8, Page: 207-220
2010
- 2Citations
- 14Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations2
- Citation Indexes2
- CrossRef2
- Captures14
- Readers14
- 14
Article Description
In the developing Drosophila trachea, extensive cell migration lays the foundation for an elaborate network of tubules to form. This process is controlled by the Drosophila fibroblast growth factor receptor, known as Breathless (Btl), whose expression is activated by the Trachealess (Trh) and Tango (Tgo) basic helix-loop-helix (bHLH)-PAS transcription factors. We previously identified the jing zinc finger transcription factor as a gene sensitive to the dosage of bHLH-PAS transcriptional activity and showed that its mutations interact genetically with those of trh and btl. Here, we demonstrate that jing is required for btl expression in the branching trachea and dominantly interacts with known regulators of btl expression, including the ETS and POU transcription factors, pointed, and drifter/ventral veinless, respectively. Furthermore, the zinc fingercontaining C-terminus of Jing associates with a btl tracheal enhancer in a Trh/Tgo-dependent manner in chromatin immunoprecipitation assays in vitro and interferes with btl in vitro and in vivo. Together, our results support a model by which Jing/Trh/Tgo complexes regulate btl transcript levels during primary tracheal branching. © Springer-Verlag 2010.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=78651336294&origin=inward; http://dx.doi.org/10.1007/s00427-010-0342-4; http://www.ncbi.nlm.nih.gov/pubmed/21061018; https://link.springer.com/10.1007/s00427-010-0342-4; http://www.springerlink.com/index/10.1007/s00427-010-0342-4; http://www.springerlink.com/index/pdf/10.1007/s00427-010-0342-4; https://dx.doi.org/10.1007/s00427-010-0342-4; https://link.springer.com/article/10.1007/s00427-010-0342-4
Springer Science and Business Media LLC
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know