Histological changes secondary to wire coil placement in breast tissue and lymph nodes
Virchows Archiv, ISSN: 1432-2307, Vol: 473, Issue: 3, Page: 285-291
2018
- 2Citations
- 3Captures
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Article Description
We describe the histological and immunohistochemical features of the changes produced by spiral coil localization wires in the breast parenchyma and lymph nodes of a total of 100 patients undergoing surgery for different breast lesions. Coil wires produced cystic lesions containing a hyaline, mucous-like, PAS-negative fluid. Cavities were lined by cells of variable morphology ranging from synovial-like cells (with a conspicuous epithelial appearance) to mononuclear or multinucleate histiocytic cells that expressed CD68, but were negative for keratins. CD3-positive/CD8-positive T lymphocytes predominated in the inflammatory reaction. Pathologists should be aware of these changes in order to differentiate coil-related lesions from other granulomatous or epithelial lesions, including mucocele-like and ductal carcinoma in situ lesions.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85049584745&origin=inward; http://dx.doi.org/10.1007/s00428-018-2399-9; http://www.ncbi.nlm.nih.gov/pubmed/29984379; http://link.springer.com/10.1007/s00428-018-2399-9; https://dx.doi.org/10.1007/s00428-018-2399-9; https://link.springer.com/article/10.1007/s00428-018-2399-9
Springer Science and Business Media LLC
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