Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection
Human Genetics, ISSN: 0340-6717, Vol: 123, Issue: 1, Page: 93-95
2008
- 62Citations
- 14Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations62
- Citation Indexes62
- 62
- CrossRef47
- Captures14
- Readers14
- 14
Article Description
Asthma is a complex trait which is influenced by environmental and genetic factors. In a recent genome-wide association study on asthma in European subjects, novel associations were reported between 17q21 single nucleotide polymorphisms (SNPs) and childhood asthma. We performed an association study with the ten SNPs that showed the strongest association in a French-Canadian asthmatic familial collection. Family-based association tests revealed significant associations for eight SNPs (0.005 < P < 0.017) and for two haplotypes (P = 0.0004 and 0.002), confirming the 17q21 as an asthma locus. © Springer-Verlag 2007.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=38949188741&origin=inward; http://dx.doi.org/10.1007/s00439-007-0444-x; http://www.ncbi.nlm.nih.gov/pubmed/17992541; http://link.springer.com/10.1007/s00439-007-0444-x; http://www.springerlink.com/index/10.1007/s00439-007-0444-x; http://www.springerlink.com/index/pdf/10.1007/s00439-007-0444-x; https://dx.doi.org/10.1007/s00439-007-0444-x; https://link.springer.com/article/10.1007/s00439-007-0444-x
Springer Science and Business Media LLC
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