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Enzymatic synthesis of poly-l-lactide-co-glycolide in the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate

Bioprocess and Biosystems Engineering, ISSN: 1615-7591, Vol: 33, Issue: 9, Page: 1095-1101
2010
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Article Description

This article reports the lipase-catalyzed ring-opening copolymerization of l-lactide (LLA) and glycolide using the commercially available ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate as solvent media. Candida antarctica lipase B, immobilized in an acrylic support was used as biocatalyst. The reaction temperature had a direct influence on yields and molecular weights of the copolymers as well as LLA incorporation. The materials presented semi-crystalline structures assessed by DSC and powder XR diffraction analyses. © 2010 Springer-Verlag.

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