Moxibustion for the treatment of chemotherapy-induced leukopenia: a systematic review of randomized clinical trials
Supportive Care in Cancer, ISSN: 1433-7339, Vol: 23, Issue: 6, Page: 1819-1826
2015
- 21Citations
- 31Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations21
- Citation Indexes21
- 21
- CrossRef6
- Captures31
- Readers31
- 31
Article Description
Purpose: The purpose of this study is to assess the efficacy of moxibustion as a treatment of chemotherapy-induced leukopenia. Methods: Twelve databases were searched from their inception through June 2014, without a language restriction. Randomized clinical trials (RCTs) were included if moxibustion was used as the sole treatment or as a part of a combination therapy with conventional drugs for leukopenia induced by chemotherapy. Cochrane criteria were used to assess the risk of bias. Results: Six RCTs with a total of 681 patients met our inclusion criteria. All of the included RCTs were associated with a high risk of bias. The trials included patients with various types of cancer receiving ongoing chemotherapy or after chemotherapy. The results of two RCTs suggested the effectiveness of moxibustion combined with chemotherapy vs. chemotherapy alone. In four RCTs, moxibustion was more effective than conventional drug therapy. Six RCTs showed that moxibustion was more effective than various types of control interventions in increasing white blood cell counts. Conclusions: There is low level of evidence based on these six trials that demonstrates the superiority of moxibustion over drug therapies in the treatment of chemotherapy-induced leukopenia. However, the number of trials, the total sample size, and the methodological quality are too low to draw firm conclusions. Future RCTs appear to be warranted.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84933568330&origin=inward; http://dx.doi.org/10.1007/s00520-014-2530-7; http://www.ncbi.nlm.nih.gov/pubmed/25471180; http://link.springer.com/10.1007/s00520-014-2530-7; https://dx.doi.org/10.1007/s00520-014-2530-7; https://link.springer.com/article/10.1007/s00520-014-2530-7
Springer Science and Business Media LLC
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