A 2-year prospective study of bone metabolism and bone mineral density in adolescents with anorexia nervosa
Journal of Neural Transmission, ISSN: 0300-9564, Vol: 114, Issue: 12, Page: 1611-1618
2007
- 40Citations
- 40Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations40
- Citation Indexes38
- 38
- CrossRef24
- Policy Citations2
- Policy Citation2
- Captures40
- Readers40
- 40
Article Description
Osteopenia and osteoporosis are complications of adolescent anorexia nervosa (AN) and may result in a permanent deficit of bone mass in adulthood. It is still unclear if a complete catch-up in bone mineral density (BMD) is possible after weight rehabilitation in AN. Methods. We investigated bone formation (bAP, PICP), bone resorption (CTX) and BMD (lumbar spine, femoral neck) along with endocrinological parameters in 19 girls with AN (14.4 ± 1.6 years) and in 19 healthy controls for 2 years after inpatient re-feeding. Results. Re-feeding normalised bone formation activity in patients. The pattern of bone turnover in patients after 2 years was similar to the pattern healthy controls had shown 2 years before. BMD of patients was significantly lower than in controls and did not change throughout the entire study. Conclusions. Weight rehabilitation leads to prolonged normalization of bone turnover in adolescent AN. Since we could not observe a "catch up" effect in BMD of girls with AN in a 2-year follow-up, BMD of these patients needs to be carefully monitored until adulthood to detect early osteoporosis. © 2007 Springer-Verlag.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=36749020098&origin=inward; http://dx.doi.org/10.1007/s00702-007-0787-4; http://www.ncbi.nlm.nih.gov/pubmed/17676429; http://link.springer.com/10.1007/s00702-007-0787-4; http://www.springerlink.com/index/10.1007/s00702-007-0787-4; http://www.springerlink.com/index/pdf/10.1007/s00702-007-0787-4; https://dx.doi.org/10.1007/s00702-007-0787-4; https://link.springer.com/article/10.1007/s00702-007-0787-4
Springer Science and Business Media LLC
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