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Targeting intracellular signalling pathways

Onkologe, ISSN: 0947-8965, Vol: 13, Issue: 1, Page: 32-45
2007
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Targeting intracellular pathways is a promising new approach in cancer treatment. During tumorigenesis key elements of the intracellular signalling network are altered in their biological activity. Low-molecular-weight compounds directed against the active motifs of kinases or other regulatory proteins therefore open up new therapeutic options, especially in combination with established cancer therapies. © 2006 Springer Medizin Verlag.

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