Assessment of the pectolinarin content and the radical scavenging-linked antiobesity activity of Cirsium setidens Nakai extracts
Food Science and Biotechnology, ISSN: 1226-7708, Vol: 24, Issue: 6, Page: 2235-2243
2015
- 10Citations
- 12Captures
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Article Description
Cirsium setidens Nakai contains bioactive compounds that exert biological activities. Method validation for analysis of the pectolinarin content in Cirsium setidens extracts (CSE) and radical scavenging-linked antiobesity activities using 3T3-L1 cells and C57BL/6 mice were performed. The pectolinarin content of CSE was 2.81±0.01 mg/g with a high degree of linearity in calibration curves (R=0.9999). CSE exhibited free radical-scavenging activities and a reducing power. CSE and pectolinarin inhibited lipid accumulation during adipogenesis of 3T3-L1 cells via down-regulation of adipogenic transcription factors. CSE supplementation suppressed body weight in C57BL/6 mice fed a high fat diet and reduced plasma total cholesterol, triglyceride, insulin, and glucose levels. Pectolinarin-enriched CSE can be considered as a good source of natural antioxidants and antiobesity ingredients.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84948957040&origin=inward; http://dx.doi.org/10.1007/s10068-015-0298-2; http://link.springer.com/10.1007/s10068-015-0298-2; http://link.springer.com/content/pdf/10.1007/s10068-015-0298-2; http://link.springer.com/content/pdf/10.1007/s10068-015-0298-2.pdf; http://link.springer.com/article/10.1007/s10068-015-0298-2/fulltext.html; https://dx.doi.org/10.1007/s10068-015-0298-2; https://link.springer.com/article/10.1007/s10068-015-0298-2
Springer Science and Business Media LLC
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