Letter to editor: Serum concentration–guided intravenous magnesium sulfate administration for neuroprotection in patients with aneurysmal subarachnoid hemorrhage: A retrospective evaluation of a 12-year single-center experience.
Neurosurgical Review, ISSN: 1437-2320, Vol: 47, Issue: 1, Page: 193
2024
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Letter Description
This critique examines a 12-year retrospective study on serum magnesium concentration-guided administration of magnesium sulfate in 548 patients with aneurysmal subarachnoid hemorrhage (aSAH). The study reported that maintaining serum magnesium levels between 2 and 2.5 mmol/L reduced rates of delayed cerebral infarction and improved clinical outcomes. However, limitations due to its retrospective nature, single-center design, and unequal treatment group sizes may affect generalizability. Future multicentric randomized controlled trials are recommended to validate these findings and refine magnesium dosing strategies for aSAH treatment.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85191391928&origin=inward; http://dx.doi.org/10.1007/s10143-024-02431-y; http://www.ncbi.nlm.nih.gov/pubmed/38662220; https://link.springer.com/10.1007/s10143-024-02431-y; https://dx.doi.org/10.1007/s10143-024-02431-y; https://link.springer.com/article/10.1007/s10143-024-02431-y
Springer Science and Business Media LLC
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