Subcutaneous gentamycin implant to reduce wound infections after loop-ileostomy closure: A randomized, double-blind, placebo-controlled trial
Diseases of the Colon and Rectum, ISSN: 0012-3706, Vol: 48, Issue: 11, Page: 2025-2031
2005
- 46Citations
- 32Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations46
- Citation Indexes44
- 44
- CrossRef33
- Clinical Citations1
- PubMed Guidelines1
- Policy Citations1
- Policy Citation1
- Captures32
- Readers32
- 32
Article Description
BACKGROUND: After loop-ileostomy closure subcutaneous wound infection is the most frequent postoperative complication. Implantation of local antibiotics has been shown to reduce the incidence of wound infection after different surgical procedures, therefore, a subcutaneous application of a gentamycin implant may also decrease infection rate after ileostomy-closure. METHODS: We conducted a randomized, double-blind, placebo-controlled trial to evaluate the effectiveness of a subcutaneous gentamycin-collagen implant to reduce wound infection after loop-ileostomy closure. Patients had the same perioperative treatment and standardized anastomotic and closure technique. A collagen sponge with gentamycin was used in the treatment group and an identical collagen implant without antibiotics was used in the placebo group. RESULTS: Eighty patients (40 per group) were included. There was no difference between the groups with respect to demographics or in the postoperative course. The total wound infection rate was 10 percent with no difference between the gentamycin (n = 4) and the collagen group (n = 4) (P = 1.0). CONCLUSION: Subcutaneous implantation of a gentamycin sponge yields no clinically relevant reduction of the wound infection rate after loop-ileostomy closure so that routine use is not recommended in this procedure. © The American Society of Colon and Rectal Surgeons.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=29844453969&origin=inward; http://dx.doi.org/10.1007/s10350-005-0164-z; http://www.ncbi.nlm.nih.gov/pubmed/16228839; https://journals.lww.com/00003453-200548110-00003; https://dx.doi.org/10.1007/s10350-005-0164-z; https://journals.lww.com/dcrjournal/Abstract/2005/48110/Subcutaneous_Gentamycin_Implant_to_Reduce_Wound.3.aspx; http://www.springerlink.com/index/10.1007/s10350-005-0164-z; http://www.springerlink.com/index/pdf/10.1007/s10350-005-0164-z
Ovid Technologies (Wolters Kluwer Health)
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