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TransPrEP: Results from the Pilot Study of a Social Network-Based Intervention to Support PrEP Adherence Among Transgender Women in Lima, Peru

AIDS and Behavior, ISSN: 1573-3254, Vol: 25, Issue: 6, Page: 1873-1883
2021
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Article Description

We conducted a pilot randomized controlled trial of a social network-based intervention to promote PrEP adherence among transgender women (TW) in Lima, Peru. We enrolled 89 TW from six social networks and cluster-randomized them 1:1 to standard of care (n = 44) or the TransPrEP intervention (n = 45). Core workshops discussed strategies to support PrEP adherence and defined group adherence objectives. Maintenance workshops discussed participants’ experiences taking PrEP and collective adherence goals. At 3-month follow-up, we evaluated 40 participants and obtained 29 hair samples for tenofovir level measurements. Though no significant differences were observed, 36.4% (4/11) of participants of TransPrEP participants and 10.0% (1/10) of control participants had tenofovir levels > 0.023 ng/mg, consistent with ≥ 4 doses per week. 81.8% (9/11) of intervention and 40.0% (4/10) of control participants had any detectable tenofovir in their hair. Pilot assessment of our network-based intervention suggested a trend towards improved PrEP adherence, measured objectively, for TW in Peru.

Bibliographic Details

Clark, Jesse; Reisner, Sari; Perez-Brumer, Amaya; Huerta, Leyla; Sanchez, Hugo; Moriarty, Kathleen; Luque, Maria Mamani; Okochi, Hideaki; Salazar, Ximena; Mimiaga, Matthew; Sanchez, Jorge; Gandhi, Monica; Mayer, Kenneth H; Lama, Javier R

Springer Science and Business Media LLC

Psychology; Medicine

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